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Image Search Results
Journal: BMC Neuroscience
Article Title: Sex-specific cypermethrin-induced hippocampal neurotoxicity is associated with alterations in signaling molecules for antioxidant defense, membrane integrity, apoptosis, and GABAergic integrity
doi: 10.1186/s12868-025-00988-y
Figure Lengend Snippet: GnRH ( A ), Na+/K + ATPase ( B ), PGE-2 ( C ), and COX-2 concentrations in the brains of Male and Female Wistar rats exposed to corn oil (control), low dose (6.25 mg/kg), and high dose (12.5 mg/kg) of cypermethrin, respectively. Asterisk (*) indicates significant ( P < 0.05) weight loss. Bars are mean ± SD
Article Snippet: The following kits were used: GnRH (Sandwich ELISA, Kit #MBS269200, MyBioSource),
Techniques: Control
Journal: Disease Models & Mechanisms
Article Title: A novel and efficient murine model of Bietti crystalline dystrophy
doi: 10.1242/dmm.049222
Figure Lengend Snippet: Morphological changes of photoreceptors and RPE in Cyp4v3 −/− mice. (A) Representative H&E images of retinal sections. The black arrowheads indicate the cavity in IS/OS. The red line indicates the thickness of the ONL. (B) Phalloidin (green) staining in RPE-choroid complex flatmounts of 12-month-old wild-type (WT) and Cyp4v3 −/− mice. (C) Retinal sections were stained for the remarkable markers of cone photoreceptors (Cone-arrestin, M-Opsin, S-Opsin and PNA) in 12-month-old wild-type and Cyp4v3 −/− mice. (D) Densitometric analysis of the relative level of Cone-arrestin, M-Opsin, S-Opsin and PNA in 12-month-old wild-type and Cyp4v3 −/− mice. (E) Retinal sections were stained for the remarkable markers of rod photoreceptors (rhodopsin and recoverin) in 12-month-old wild-type and Cyp4v3 −/− mice. The inner segment was labeled by NaK ATPase (red). (F) Densitometric analysis of the relative level of rhodopsin and recoverin in 12-month-old wild-type and Cyp4v3 −/− mice. Data are mean±s.d. * P <0.05, ** P <0.01, *** P <0.001 (Student’s unpaired two-tailed t -test). Scale bars: 50 µm. n =5 for each group.
Article Snippet: Antibodies used for staining were anti-phalloidin (F432, Thermo Fisher Scientific, 1:500), anti-cone arrestin (ab15282, Millipore, 1:500), anti-M-opsin (red/green opsin, ab5405, Millipore, 1:500), anti-S-opsin (blue opsin, ab5407, Millipore, 1:500), anti-peanut agglutinin (FL-1071, Vector Laboratories, 1:500), anti-rhodopsin (ab98887, Abcam, 1:500),
Techniques: Staining, Labeling, Two Tailed Test